Contact Information
Mailing Address
Prof. Tatiana Segura
420 Westwood Plaza
5531 Boelter Hall
Los Angeles, CA 90095
Lab
7524 Boelter Hall
(310) 794-2248
Office
5532-C Boelter Hall
(310) 206 3980
Protein immobilization
Growth factors in vivo exist in both soluble and immobilized forms. However, the ability of immobilized growth factors to induce signal transduction and the differences between the signaling induced by a soluble versus an immobilized growth factors have not been throughly investigated. Further, strategies to effectively immobilize growth factors will be of great interest to tissue engineering and regenerative medicine applications. Immobilized growth factors to three dimensional matrices may lead to enhanced stability and specific release kinetics. We are currently developing strategies to immobilize growth factors using biomimetic approaches.
Collaborator: Luisa Iruela-Arispe
Research
