UCLA Chemical & Biomolecular Engineering Department
UCLA Chemical & Biomolecular Engineering Department
Engineering Cell Instructive Materials
Lab: Engineering 1 Room 3024 | (310) 794-2248
Office: Boelter Hall 5532-C | (310) 206 3980 | tsegura@ucla.edu
Peer-reviewed publications
1.Catharina Adelöw, Segura, T, Jeffrey. A. Hubbell Peter Frey “The effect of enzymatically degradable poly(ethylene glycol) hydrogels on smooth muscle cell phenotype” Biomaterials 2008 29(3):314-326.
2.Segura, T and Hubbell, JA "Synthesis and in vitro Characterization of an ABC triblock copolymer for the delivery of siRNA" Bioconjugate Chemistry 2007 18(3): 736-45.
3.Segura, T, Schmokel, H, Hubbell, JA "RNA Interference Targeting Hypoxia Inducible Factor 1a Prevents Postoperative Adhesions in Rats." Journal of Surgical Research 2007 141(2) 162-170
4.Bengali, Z, Pannier, AK, Segura, T, Anderson, BC, Jang, JH, Mustoe, TA and Shea, LD “Gene delivery through cell culture substrate adsorbed DNA Complexes.” Biotechnology and Bioengineering 2005 5;90(3):290-302.
5.Segura, T; Chung, PH; Shea, LD. "DNA delivery from hyaluronic acid-collagen hydrogels via a substrate-mediated approach." Biomaterials, 2005 26 (13): 1575-1584.
6.Segura, T; Anderson, BC; Chung, PH; Webber, RE; Shull, KR; Shea, LD. "Crosslinked hyaluronic acid hydrogels: a strategy to functionalize and pattern." Biomaterials, 2005 26 (4): 359-371.
7.Segura, T, Volk MJ and Shea, LD, “Substrate-Mediated DNA Delivery: Role of the Cationic Polymer Structure and Extent of Modification.” Journal of Controlled Release, 2003 93: 69-84
8.Segura, T. and L.D. Shea. "Surface-Tethered DNA Complexes for Enhanced Gene Delivery" Bioconjugate Chemisty 2002 13(3): 621-9
Book Chapters
1.Segura, T. and L.D. Shea, “Biomaterials for non-viral gene delivery” In Annual Reviews in Material Science, ed. Samuel I. Stupp, Annual Reviews, Palo Alto, CA 31:25-46, 2001
2.Segura, T, Anderson, BC, and Shea, LD, “Biodegradable materials for DNA delivery” in Handbook of Biodegradable Polymeric Materials and Their Applications, Submitted 2003
3.Segura, T "Formulations and Delivery Limitations of Nucleic Acid Based Therapies" in Handbook of Pharmaceutical Biotechnology 7.3:1013-1059, 2007